With the onset of Cloud computing, there is a big paradigm shift underway; instead of developing a web app in your IT center, you will be developing a Cloud application to be deployed in the Cloud.
With increasing adoption, the day is not far when this technology will be commoditized with even open source offerings. Though it is currently the preserve of only the biggies, every IT organization however small is also realizing the benefits of this technology and a lot of vendors are busy building Cloud Computing solutions. Soon it will be the purview of the masses.
Hang on to your seats, it is going to be a roller coaster of a ride.